Publications

Acknowledments of DanORC in publications, see here.
* Related papers by DanORC partners

Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Almind K, Hansen L, Jorgense T, Pedersen O, Hansen T. Studies of CTNNBL and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18.014 Danes. BMC Medical Genetics 2009, 10: 17. Read abstract here.

Bosch G, Verbrugghe A, Hesta M, Holst JJ, van der Poel AFB, Janssens GPJ, Hendriks WH. The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs. British Journal of Nutrition 2009; Jan 15, 2009; 102: 318-325. Read abstract here.

Brader L, Holm L, Mortensen L, Thomsen C, Astrup A, Holst JJ, de Vrese M, Schrezenmeir J, Kermansen K. Acute effects of casein on postprandial lipemia and incretin responses in type 2 diabetic subjects. Nutrition, Metabolism & Cardiovascular Diseases, 2009 May 25 [ahead of print]. Read abstract here.

Hasselbalch AL, Ängquist L, Christiansen L, Heitmann BL, Kyvik KO, Sørensen TIA. Variants in FTO and MC4R influence dietary intake. Submitted Aug 2009.

Hasselbalch AL, Heitmann BL, Kyvik KO, Sørensen TIA. Individually modifiable dietary composition and body fatness in monozygotic twins. Submitted May 2009.

Hlebowicz J, Hlebowicz A, Lindstedt S, Björgell O, Höglund  Darwiche, Almér L-O. Effect of 1g and 3 g cinnamon on postprandial blood glucose, insulin, GIP, GLP-1, ghrelin, gastric emptying , and satiety in healthy subjects. American Journal of Clinical Nutrition 2009; 89: 815-821. Read abstract here.

Jakobsen MU, Overvad K. Observational epidemiological studies on intake of trans fatty acids and risk of ischaemic heart disease. In: Destaillats F, Sébédio JL, Dionisi F, Chardigny JM, eds. Trans fatty acids in human nutrition. Bridgwater, England: The Oily Press, 2009:255-306.

*Jakobsen MU, Overvad K, Dyerberg J, Heitmann BL. Intake of ruminant trans fatty acids and risk of coronary heart disease. International Journal of Epidemiology 2008; 37 (1): 182-184. Read abstract here.

Liaset B, Madsen L, Hao Q, Mellgren G, Marshall HU, Espe M, Frøyland K, Kristiansen K. Fish protein hydrolysate elevates plasma bile acids and reduces visceral adipose tissue mass in rats. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2009; 1791: 254-262. Read abstract here.

Mercader J, Ribot J, Murano I, Cinti S, Madsen L, Kristiansen K, Bonet ML, Palou A. Haploinsufficiency of the retinoblastoma protein gene reduces diet-induced obesity, insulin resistance and hepatostatosis in mice. American Journal of Physiology –Endocrinology & Metabolism; 2009; 297: E184-93. Read abstract here.

Mingrone G, Nolfe G, Gissey GC, Iaconelli A, Leccesi L, Guidone C, Nanni G, Holst JJ. GIP and GLP-1 circadian rhythm and pulsatility in glucose tolerant and in typoe 2 diabetic subjects after malabsorptive bariatric surgery. Diabetologia 2009; 52: 873-881. Read abstract here.

Mortensen LS, Hartvigsen ML, Brader LJ, Astrup A, Schrezenmeir J, Holst JJ, Thomsen C, Hermansen K. Differential effects of protein quality on postprandial lipemia in response to a fat-rich meal in type 2 diabetes: comparison of whey, casein, gluten, and cod protein. Americal Journal of Clinical Nutrition 2009; 90 (1): 41-48. Read abstract here.

Nielsen BM, Nielsen MM, Toubro S, Pedersen O, Astrup A, Sørensen TI, Jess T, Heitmann BL. Influence of past and current body size on validity of reported intake among middle-aged Danish men. Submitted 2009.

Severinsen MT, Kristensen SR, Johnsen SP, Dethlefsen C, Tjønneland A, Overvad K. Anthropometry, Body Fat, and Venous Thromboembolism: A Danish Follow-Up Study. Circulation. 2009 Nov 10;120(19):1850-7. Epub 2009 Oct 26.. Read abstract here.

Sørensen TI. Conference on "Multidisciplinary approaches to nutritional problems". Symposium on "Diabetes and health". Challenges in the study of causation of obesity. Proceedings of the Nutrition Society 2009 Feb;68(1): 43-54. Read abstract here.

Zijlstra N, Mars M, de Wijk RA, Westerterp-Plantenga MS, Holstr JJ, de Graaf  C. Effect of viscosity on appetite and gastro-intestinal hormones. Physiology & Behaviour, 2009; 97(1):68-75. Read abstract here.

Zimmermann E, Kring SI, Berentzen TL, Holst C, Pers TH, Hansen T, Pedersen O, Sørensen TI, Jess T. Fatness-Associated FTO Gene Variant Increases Mortality Independent of Fatness – in Cohorts of Danish Men. PLoS ONE 2009 4(2): e4428. Read abstract here.

Zobel DP, Andreasen CH, Grarup N, Eiberg H, Sørensen TI, Sandbæk A, Lauritzen T, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T. Variants near MC4R are associate with obesity and influence obesity-related quantitative traits in a population of middle-ages people: studies of 14.940 Danes. Diabetes 2009, 58: 757-764. Read abstract here.

Ølholm J, Paulsen SK, Richelsen B, Pedersen SB. Anti -inflammatory effect of resveratrol on IL-1β and FFA-induced adipokine production in human adipose tissue. Submitted 2009.

Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Sørensen TI, Hansen L, Almind K, Jørgensen T, Pedersen O, Hansen T. Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes. PLoS ONE 2008 6;3(8):e2872. Read abstract here.

Andreasen CH, Stender-Petersen KL, Mogensen MS, Torekov SS, Wegner L, Andersen G, Nielsen AL, Albrechtsen A, Borch-Johnsen K, Rasmussen SS, Clausen JO, Sandbæk A, Lauritzen T, Hansen L, Jørgensen T, Pedersen O, Hansen T. Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. Diabetes 2008; 57: 95-101. Read abstract here.

Dam, Thea, Jensen, Jørgen Dejgård & Kærgård, Niels. Obesity, social inequality and economic rationality: an overview. Food Economics - Acta Agriculturae Scandinavica, 2008. Read abstract here.

Due A, Larsen TM, Hermansen K, Stender S, Holst JJ, Toubro S, Martinussen T, Astrup A. Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monounsaturated-fat, low-fat, and control diets. American Journal of Clinical Nutrition 2008; 87: 855-62. Read abstract here.

Ellrichmann M, Kapelle M, Ritter PR, Holst JJ, Herzig K-H, Schmidt WE, Schmitz F, Meier JJ. Orlistat Inhibition of Intestinal Lipase Acutely Increases Appetite and Attenuates Portpandrial Clucagon-Like Peptide-1-(7-36)-Amide-1, Cholecystokinin, and Peptide YY Concentrations. The Journal of Clinical Endocrinology and Metabolism 2008 93(10):3995-8. Read abstract here.

Grarup N, Andersen G, Krarup NT, Albrechtsen A, Schmitz O, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen O. Association testing of novel type 2 diabetes risk-alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes. Diabetes 2008; 57 (9): 2534-2540. Read abstract here.

Grarup N, Andreasen CH, Andersen MK, Albrechtsen A, Sandbæk A, Lauritzen T, Borch-Johnsen K, Jørgensen T, Schmitz O, Hansen T, Pedersen O. The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects. Journal of Clinical Endocrinology & Metabolism 2008; 93: 2294-2299. Read abstract here.

Grarup N, Stender-Petersen KL, Andersson EA, Jørgensen T, Borch-Johnsen K, Sandbæk A, Lauritzen T, Schmitz O, Hansen T, Pedersen O. Association of variants in the sterol regulatory element-binding factor 1 gene (SREBF1) with type 2 diabetes, glycemia, and insulin resistance – a study of 15,734 Danish subjects. Diabetes 2008;  57(4): 1136-42. Read abstract here.

Hasselbalch AL, Silventoinen K, Keskitalo K, Pietiläinen K, Rissanen A, Heitmann BL, Kyvik KO, Sørensen TIA, Kaprio J. Twin study of the heritabillity of eating bread in Danish and Finnish men and women. Submitted Nov 2008.

Madsen L, Liaset B, Kristiansen K. Macronutrients and obesity: views, news and reviews. Future Lipidology 2008; 3: 43-74. Read abstract here.

Madsen L, Pedersen LM, Liaset B, Ma T, Petersen RK, van den Berg S, Pan J, Müller-Decker K, Dülsner ED, Kleemann R, Kooistra T, Døskeland SO, Kristiansen K. cAMP-dependent Signaling Regulates the Adipogenic Effect of n-6 Polyunsaturated Fatty Acids. Journal of Biological Chemistry 2008; 283 (11): 7196-205. Read abstract here.

Muscelli E, Mari A, Casolaro A, Camastra S, Seghieri G, Gastaldelli A, Holst JJ, Ferrannini E. Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients. Diabetes 2008; 57: 1340-1348. Read abstract here.

Nilsson AC, Östman EM, Holst JJ, Björck IME. Including Indigestible Carbohydrates in the Evening Meal of Healthy Subjects Improves Glucose Tolerance, Lowers Inflammatory Markers, and Increases Satiety after a Subsequent Standardized Breakfast. The Journal of Nutrition 2008; 138: 732-39. Read abstract here.

Olsen SF, Østerdal ML, Salvig JD, Mortensen LM, Rytter R, Secher NJ, Henriksen TB. Fish Oil intake compared with olive oil intake in late pregnancy and asthma in the offspring: 16 y of registry-based follow-up from a randomized controlled trial. American Journal of Nutrition 2008; 88: 167-75. Read abtract here.

Pedersen SB, Ølholm J, Paulsen SK, Bennetzen M, Richelsen B. Low Sirt1 expression, which is upregulated by fasting in human adipose tissue. International Journal of Obesity 2008;32:1250-55. Read abstract here.

Petersen RK, Madsen L, Pedersen LM, Hallenborg P, Hagland H, Viste K, Kristiansen K. Cyclic AMP (cAMP)-Mediated Stimulation of Adipocyte Differentiation Requires the Synergistic Action of Epac- and cAMP-Dependent Protein Kinase-Dependent Processes. Molecular and Cellular Biolology 2008; 28(11): 3804-3816. Read abstract here.

* Pischon T, Boeing H, Hoffmann K, Bergmann M, Schulze MB, Overvad K, van der Schouw YT, Spencer E, Moons KG, Tjønneland A, Halkjaer A, Jensen MK, Stegger J, Clavel-Chapelon F, Boutron-Ruault MC, Chajes V, Linseisen J, Kaaks R, Trichopoulou A, Trichopoulos D, Bamia C, Sieri S, Palli D, Tumino R, Vineis P, Panico S, Peeters PH, May AM, Bueno-de-Mesquita HB, van Duijnhoven FJ, Hallmans G, Weinehall L, Manjer J, Hedblad B, Lund E, Agudo A, Arriola L, Barricarte A, Navarro C, Martinez C, Quirós JR, Key T, Bingham S, Khaw KT, Boffetta P, Jenab M, Ferrari P, Riboli E. General and Abdominal Adiposity and Risk of Death in Europe. New England Journal of Medicine 2008; 359 (20): 2105-2120. Read abstract here.

* Sparsø T, Andersen G, Albrechtsen A, Jørgensen T, Borch-Johnsen K, Sandbæk A, Lauritzen T, Wasson J, Permutt MA, Glaser B, Madsbad S, Pedersen O, Hansen T. Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation. Diabetologia 2008; 51 (9): 1646-52. Read abstract here.

Sørensen LB, Cueto HT, Andersen MT, Bitz C, Holst JJ, Rehfeld JF, Astrup A. The effect of Salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake. American Journal of Clinical Nutrition 2008; 87 (5): 1163-69. Read abstract here.

Madsen L, Petersen RK, Kristiansen K. Regulation of adipocyte differentiation and function by macronutrients. Obesity: Genomics and Postgenomics (Eds. Karine Clément and Thorkild I. A. Sørensen), pp. 429-449, 2007.